Professor Morag Young is a leading authority on the role of hormones in cardiovascular disease, with a particular focus on mineralocorticoid receptor (MR) pathophysiology. This includes the study of the heart’s circadian clock and how disrupted circadian rhythms, and activation of the MR could damage our hearts. More broadly, she is interested in the intersection between cardiovascular disease and endocrinology, and how cellular mechanisms lead to cardiac fibrosis and inflammation, and cardiac dysfunction (heart failure).

Morag heads the Cardiovascular Endocrinology laboratory at the Institute. She is also a supervisor at Monash, La Trobe and Deakin Universities, and the University of Melbourne.

Her discovery research program has identified novel mechanisms of MR action in cardiovascular disease that include cell-selective pathways in macrophages, cardiomyocytes and endothelial cells. Most recently, her work has identified a highly novel interaction of the MR with the molecular clock in the pathogenesis of cardiovascular disease.

She is translating her molecular and preclinical findings into drug discovery programs and biomarker identification in heart failure patients and patients with endocrine forms of hypertension. Morag’s novel data for MR signalling and circadian function is being extended to new models of cardiovascular disease, clinical biomarker studies, drug discovery and translation through independently funded research programs. New data showing the independent role of of poor sleep and shift work on blood pressure was recently published in Nature Communications.

She is also a CoChief Investigator on the Primary Aldosterone Centre of Excellence (PACE) which is funded by an NHMRC CRE Grant and leads the Scientific Advisory Group.
Professor Young has authored over 120 peer-reviewed scientific papers, invited reviews and book chapters and serves as Deputy Editor for The Journal of Endocrinology, The Journal of Molecular Endocrinology and is a member of the editorial board for The Journal of Steroid Biochemistry and Molecular Biology. Morag is a member of faculty for the US Endocrine Society and serving on the program committee for the Endocrine Society of Australia.

Morag is passionate about helping to champion diversity and gender equity in science. She is a member of the AAMRI Gender Equity Diversity and Inclusion Committee, Co-Chairs the Baker Institute’s Gender Equity and Diversity Committee and is co-leading the Institute in its application for a Silver Award in the Athena SWAN Science in Australia Gender Equity (SAGE) program. In 2020, she became the inaugural recipient of the Alice Baker and Eleanor Shaw Gender Equity Fellowship for senior female researchers. Morag enjoys promoting science and a career in STEM to girls and young women and mentoring early career scientists, so they achieve their potential. She also actively promotes heart health and research news through speaking engagements in rural and regional community groups within country Victoria.