Laboratory
Molecular Proteomics
Auriane graduated from the University of Lorraine (France) in 2020 as an Agricultural Engineer specialising in biotechnology and plant engineering. The same year, she also completed her MBA at Nancy School of Management (France), giving her a better insight into industry organisation.
Auriane gained extensive international research experience through internships in both academic and industry environments, including Peter McCallum Cancer Centre in 2018, Baker Institute (Cardiac Cellular Systems) in 2019 and the Research and Innovation department at L’Occitane en Provence (France) in 2020.
With a keen interest in extracellular vesicles and quantitative proteomics, Auriane joined the Molecular Proteomics laboratory at the Baker Institute in 2021 as a Master’s student. In this project, she developed a highly scalable and autologous drug delivery system using red blood cell-derived nanovesicles and described their innate anti-fibrotic activity for the first time.
In 2023, as a recipient of the Australian Government Research Training Program (RTP) Scholarship, Auriane continued in the Molecular Proteomics laboratory as a PhD student, developing integrated proteomic and functional strategies to maximise the therapeutic potential of cell-derived nanovesicles for cardiac repair. Her research combines quantitative mass spectrometry with scalable nanovesicle production and biomaterial-based delivery, defining vesicle cargo and the molecular pathways that underpin therapeutic activity. She has applied proteomics to characterise extracellular-matrix and mechanosensitive signalling responses across engineered cell environments, and to resolve fibrosis-associated protein networks in primary cardiac fibroblasts. These molecular findings are linked directly to functional anti-fibrotic assays, including myofibroblast activation, collagen-gel contraction, actomyosin organisation and cell-matrix adhesion. Her current work integrates proteomic discovery with an adhesive silk hydrogel patch that enables localised, sustained nanovesicle delivery to injured myocardium, providing a translational platform to preserve vesicle bioactivity, promote anti-fibrotic remodelling and improve cardiac repair.
Awards
- Full Research Training Program (RTP) scholarship (2023)
- Baker Institute Student No bell prize winner (2022)
