Project title: The long-term effects of a peer-led lifestyle intervention program on diabetes progression and cardiovascular risk: the Kerala Diabetes Prevention Program (K-DPP)
This NHMRC-funded research (ID 1160283) examines the long-term effects of a peer-led lifestyle intervention program, the Kerala Diabetes Prevention Program (K-DPP), on diabetes progression and cardiovascular risk. This project involves the 9-year follow-up of participants in the original K-DPP trial in Kerala, India which has been implemented over a 12-month period in two districts within the state of Kerala, India.
The aim of this project is to evaluate the long-term effects of the K-DPP. The objectives are:
- To measure the program effectiveness of K-DPP at 9 years from study recruitment.
- To undertake an economic evaluation of K-DPP to determine the long-term value and return on investment.
- To evaluate community engagement and program sustainability of K-DPP groups and related community activities after 9 years.
K-DPP has extensive data on behavioural/lifestyle, psychosocial, medical history and family history of disease, health service utilization, anthropometric and biochemical measures, retinal vasculature, and ECG measures for middle-aged adults at elevated risk of diabetes at baseline. The data was collected at baseline, 12 months, 24 months, and now at 9 years after intervention.
Collaborating institution
Baker Heart and Diabetes Institute, Melbourne, Australia; Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) in Trivandrum, Kerala
Chief investigators
Brian Oldenburg, Ajay Mahal, Fisher Edwin B, Jeemon P, KR Thankappan, Nitin Kapoor, Robyn Tapp and Sathish Thirunavukkarasu
Associate investigators
Chris Owen, GK Mini, James Donovan Best, Jonathan Shaw, Mojtaba Lotfaliany Abrand Abadi, Pilvikki Absetz, Sajitha B, Zahra Aziz
PhD students
Dr Abha Shresta, Getu Demissie
Current status
Data collection in the final stages
This project welcomes all Honours, Masters, and PhD students.
Selected publications
- Cluster randomised controlled trial of a peer-led lifestyle intervention program: study protocol for the Kerala diabetes prevention program
BMC Public Health 2013 Nov 4; 13:1035 - Cultural adaptation of a peer-led lifestyle intervention program for diabetes prevention in India: the Kerala diabetes prevention program (K-DPP)
BMC Public Health 2018 Jan 4;17(1):974 - A peer-support lifestyle intervention for preventing type 2 diabetes in India: A cluster-randomized controlled trial of the Kerala Diabetes Prevention Program
PLoS Med. 2018 Jun 6;15(6): e1002575 - A group-based lifestyle intervention for diabetes prevention in low- and middle-income country: implementation evaluation of the Kerala Diabetes Prevention Program
Implement Sci. 2018 Jul 18;13(1):97 - A group-based lifestyle intervention for diabetes prevention in low- and middle-income country: implementation evaluation of the Kerala Diabetes Prevention Program
Implement Sci. 2018 Jul 18;13(1):97
For more information, contact Brian Oldenburg.