Associate Professor Judy de Haan
Associate Professor Judy de Haan holds an adjunct senior lectureship in the Department of Biochemistry and Molecular Biology, Monash University.
Associate Professor de Haan has more than 20 years of experience in her speciality field of antioxidant defence against oxidative stress and disease, with more than 50 publications in her area of speciality. Her work is highly cited with a seminal first author paper describing the GPx1 knockout mouse which she created attracting well over 250 citations to date. She began her investigations in Down syndrome, premature aging and stroke, and more recently has focused on diabetic complications that have included atherosclerosis, kidney disease and retinopathy. She has shown an important role for the antioxidant enzyme glutathione peroxidase-1 in the protection against injury in diabetic complications, and has developed a targeted antioxidant strategy to lessen the burden of diabetic complications such as DAA and diabetic nephropathy. Her focus on the GPx1 mimetic, ebselen has yielded encouraging results with reductions in both DAA and DN. Her preclinical investigations hold tremendous potential for translation into humans, and this next phase of her research is anticipated to yield far better cardiovascular outcomes than previous non-selective antioxidants such as vitamins C and E.
Associate Professor de Haan's work has been supported by grants from the NHMRC, National Heart Foundation as well as numerous industry awards.